Scientist, Synthetic Biologist
Novome is building genetically engineered microbial medicines (GEMMs) that perform defined activities in the human gut to treat chronic diseases. We have developed the first platform for controlled colonization of the gut with engineered therapeutic bacteria and are applying this to multiple disease areas as well as expanding our platform capabilities. We are moving our lead program in secondary hyperoxaluria into Phase 1 clinical trials, and are actively progressing programs in IBS, IBD, and Immuno-oncology.
We are seeking scientists who are eager to push the boundaries of synthetic biology, engineering living medicines to perform robustly in a complex, dynamic environment. Scientists in this role are supported by a strain engineering team capable of converting hundreds of high-level designs into strains within weeks and an animal research team able to transform complex experimental designs into high quality data. Scientists are responsible for leading genetic design-build-test cycles on projects, while working closely in a highly collaborative, transparent environment with others with expertise in metabolic engineering, synthetic biology, gut microbiota biology, and clinical diseases and treatments to bring new therapeutic bacterial strains from conception to IND filing. Prior experience with gut microbial organisms or biology is not required.